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degeneration

/dɪˌdʒɛnəˈɹeɪʃən/
noun

  1. The process or state of growing worse, or the state of having become worse.

  2. That condition of a tissue or an organ in which its vitality has become either diminished or perverted; a substitution of a lower for a higher form of structure.

    "fatty degeneration of the liver"

  3. Gradual deterioration, from natural causes, of any class of animals or plants or any particular organ or organs; hereditary degradation of type.

Synonymsnerf, debasement, decline, degeneracy, degradation, deterioration

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