callous

/ˈkæləs/

adjective

Emotionally hardened; unfeeling and indifferent to the suffering/feelings of others.
"She was so callous that she could criticise a cancer patient for wearing a wig."
Having calluses.

noun

A hardened area of the skin (especially on the foot or hand) caused by repeated friction, wear or use.
The material of repair in fractures of bone; a substance exuded at the site of fracture, which is at first soft or cartilaginous in consistency, but is ultimately converted into true bone and unites the fragments into a single piece.
The new formation over the end of a cutting, before it puts out rootlets.

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