across

(crosswords, often in combination) A word that runs horizontally in the completed puzzle grid or its associated clue.

"I solved all of the acrosses, but then got stuck on 3 down."

From one side to the other.

"she helped the blind man across;  the river is half a mile across"

On the other side.

"If we sail off at noon, when will we be across?"

In a particular direction.

"He leaned across for a book."

To, toward or from the far side of (something that lies between two points of interest).

"Fortunately, there was a bridge across the river."

On the opposite side of (something that lies between two points of interest).

"That store is across the street."

Across from: on the opposite side, relative to something that lies between, from (a point of interest).